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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRSK1
All Species:
10.3
Human Site:
S571
Identified Species:
22.67
UniProt:
Q8TDC3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDC3
NP_115806.1
794
86753
S571
A
W
R
S
R
L
N
S
I
R
N
S
F
L
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541413
801
87720
S578
A
W
R
S
R
L
N
S
I
R
N
S
F
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5RJI5
778
85136
S555
A
W
R
S
R
L
N
S
I
R
N
S
F
L
G
Rat
Rattus norvegicus
O08679
722
80853
K500
Q
A
S
I
Q
N
G
K
D
S
T
A
P
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514667
306
34673
K86
T
G
Q
K
V
A
I
K
I
V
N
R
E
K
L
Chicken
Gallus gallus
Q9IA88
798
88848
Q553
Q
S
D
A
P
V
L
Q
V
Q
G
C
M
G
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S745
A
V
Q
Y
Q
H
G
S
A
L
Y
Q
S
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648814
861
95238
N599
L
W
K
T
R
L
T
N
I
K
N
S
F
L
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
P761
G
S
Q
I
S
H
A
P
T
E
P
V
I
R
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
K315
D
T
V
Q
Q
A
K
K
I
D
E
E
I
L
Q
Baker's Yeast
Sacchar. cerevisiae
P34244
1518
169574
N1092
L
M
N
N
D
T
D
N
N
K
I
N
T
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
98.1
N.A.
94.8
29.2
N.A.
32.1
28.3
N.A.
25.1
N.A.
48.5
N.A.
25.7
N.A.
Protein Similarity:
100
N.A.
N.A.
98.2
N.A.
95.4
44.5
N.A.
33.3
43.9
N.A.
38.5
N.A.
62.5
N.A.
37.9
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
0
N.A.
13.3
6.6
N.A.
13.3
N.A.
60
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
13.3
N.A.
20
33.3
N.A.
26.6
N.A.
86.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.9
34.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
10
0
10
0
19
10
0
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
10
0
10
0
10
0
10
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
10
10
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
37
0
0
% F
% Gly:
10
10
0
0
0
0
19
0
0
0
10
0
0
10
46
% G
% His:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
19
0
0
10
0
55
0
10
0
19
0
0
% I
% Lys:
0
0
10
10
0
0
10
28
0
19
0
0
0
10
0
% K
% Leu:
19
0
0
0
0
37
10
0
0
10
0
0
0
46
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
10
10
0
10
28
19
10
0
46
10
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
10
0
0
10
0
10
10
10
% P
% Gln:
19
0
28
10
28
0
0
10
0
10
0
10
0
10
10
% Q
% Arg:
0
0
28
0
37
0
0
0
0
28
0
10
0
10
10
% R
% Ser:
0
19
10
28
10
0
0
37
0
10
0
37
10
10
10
% S
% Thr:
10
10
0
10
0
10
10
0
10
0
10
0
10
0
0
% T
% Val:
0
10
10
0
10
10
0
0
10
10
0
10
0
0
0
% V
% Trp:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _